| Total | Matches | Wins | Draws | Losses | |||
|---|---|---|---|---|---|---|---|
| Total | 47 | 19 | (40%) | 10 | (21%) | 18 | (38%) |
| Home | 23 | 10 | (43%) | 4 | (17%) | 9 | (39%) |
| Away | 24 | 9 | (38%) | 6 | (25%) | 9 | (38%) |
| Item | Competition | Home | Away | |
|---|---|---|---|---|
| Biggest home win | Copa Sudamericana 2021 | Peñarol | 5-1 | Sport Huancayo |
| Copa Sudamericana 2021 | Peñarol | 4-0 | Corinthians | |
| Biggest away win | Copa Sudamericana 2014 | Jorge Wilstermann | 0-4 | Peñarol |
| Copa Sudamericana 2023 | River Plate | 0-4 | Peñarol | |
| Worst away defeat | Copa Sudamericana 2023 | América Mineiro | 4-1 | Peñarol |
| Copa Sudamericana 2023 | Defensa y Justicia | 4-1 | Peñarol | |
| Worst home defeat | Copa Sudamericana 2018 | Peñarol | 1-4 | Athletico Paranaense |
| Copa Sudamericana 2023 | Peñarol | 0-3 | Defensa y Justicia |
